Computer modeling of epilepsy: opportunities for drug discovery
نویسندگان
چکیده
منابع مشابه
Computer modeling of epilepsy: opportunities for drug discovery.
Analysis of the brain as a dynamical system can assist drug development for dynamical diseases such as epilepsy. The pathological trajectories that make up a seizure differ significantly from the physiological trajectories of normal brain function. These trajectories depend on parameters - conductances and time constants of ion channels and synapses - that can be modified by drugs. Drug develop...
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ژورنال
عنوان ژورنال: Drug Discovery Today: Disease Models
سال: 2016
ISSN: 1740-6757
DOI: 10.1016/j.ddmod.2017.02.007